Judd, Burke Haycock (1954) Studies of rearrangements involving heterochromatin in Drosophila melanogaster. I. A proof of variegated-type position effect at the white locus. II. A study of the heterochromatin of chromosome IV. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01152004-095338
Abstract
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The X-IV translocation, [...], is shown to contain the wild-type allele, [...], at the white locus. This [...] has been replaced with a mutant gene, w, and a comparison of R([...])/w with R(w)/w[...] shows the former to give a variegated white phenotype while the latter is completely wild-type. It is concluded that the white variegation is due to an instability in the action of [...] when it is located in the rearranged chromosome.
Cold temperature enhances variegation particularly when applied during the embryonic stages of development. A less sensitive period is found to exist during the pupal stages. These facts indicate the white gene is active during more than a single period of development.
Twelve duplication-deficiency types have been obtained by combining the left and right parts of four X-IV translocations. Tests for survival of these combinations in the haplo-IV condition give somewhat contradictory results. These results are discussed and a possible order for the fourth chromosome translocation breaks is given.
Item Type: | Thesis (Dissertation (Ph.D.)) |
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Degree Grantor: | California Institute of Technology |
Major Option: | Biology |
Thesis Committee: |
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Defense Date: | 1 January 1954 |
Record Number: | etd-01152004-095338 |
Persistent URL: | http://resolver.caltech.edu/CaltechETD:etd-01152004-095338 |
Default Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. |
ID Code: | 182 |
Collection: | CaltechTHESES |
Deposited By: | Imported from ETD-db |
Deposited On: | 28 Jan 2004 |
Last Modified: | 25 Dec 2012 14:58 |
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